DHEA (Dehydroepiandrosterone) is a natural hormone synthesized by the adrenal glands from cholesterol. In medical terms, it is a "precursor" of hormonal synthesis, like testosterone, estrogen and progesterone. Peak glandular extrusion is reached around age 21 and drops 90% by the age of 75.
How to Recognize a DHEA Deficiency
Facial expression is one of the first things that helps detect hormonal deficiency: a bloated face, heavy eyelids, dry and brittle hair. In women these effects are often accompanied by cellulite on the thighs, a paunch, as well as sparse hair growth in the pubic area and a flattened mons veneris (Venus' mound).
Women experience anxiety attacks, low spirits, low libido and sex drive, and constant, unexplained fatigue.
Who should use DHEA?
DHEA use is recommended for the elderly and individuals who experience fatigue due to diseases caused by a depressed immune system. However, persons around age 40 may begin using DHEA, since at 40 the level of hormone production is only half what it should be. This is without considering other factors such as stress, significant dietary deficiencies, sugar or alcohol abuse, smoking, drug abuse, and any other instance of excessive stress, all of which cause the body to age prematurely.
What are adequate DHEA levels in the blood and urine?
The level of DHEA should be measured as well as that of DHEA sulfate (SDHEA).
Blood DHEA: In women, a DHEA level under 200 mcg/dl (micrograms/decilitres) and 150 mcg/dl indicates a deficiency. Studies have shown that in men over 50, DHEA levels below 120 mcg/dl are correlated to a two- or threefold increase in mortality and risk of cardiovascular disease.
When testing urine after 24 hours: DHEA levels below 0.10 ng/24 hours in women and below 0.50 ng in men may indicate a deficiency.
How much DHEA should I use?
The generally-recommended dose is 25 to 50 mg a day for women, and 50 to 75 mg a day for men. Specialists recommend an initial dose of 25 mg per day, together with a blood test after two or three weeks to check the blood DHEA level, as the best way to determine the proper dosage. Men are also advised to check their PSA level, an indicator of prostate disorder.
Always ask for your physician's advice before starting to use DHEA, and never prolong the treatment without first consulting your physician.
Should I consult a physician before starting to use DHEA ?
Even though the use of hormone therapy medicines of proven effectiveness are no longer questioned, most doctors still tend to advise against its use. Practicing physicians are trained to detect disease, not to encourage healthiness; therefore, they practice healing, not preventive medicine. Viewed from the vantage point of healing, the use of hormonal supplements appears to offer benefits that are not confined to cases where a clear deficiency exists.
It must be understood that it is not the use of the medicine that is necessary, but its effects. An individual may start using a supplement if he or she observes the recommended dosages and takes the cautions into account. However, they should consult their physician regularly (i.e., GP, gynecologist or specialist) to check for abnormalities that may or may not be due to the hormonal supplement.
In other words, anyone may start using the hormone supplement of their choice without asking for their physician's permission first (as long as they do so responsibly, follow the recommended dosages and observe the cautions for use), while following their regular medical program.
Are DHEA and the hormones we buy natural substances?
DHEA and other hormones are produced by our own glands and are therefore not medicinal products. This is why hormones do not have any contraindications as opposed to synthetic medicines. They are produced simply by reproducing their exact molecular structure in a laboratory, using today's accurate procedures.
How are hormones "produced"?
There are two ways of producing a hormone: through "hemi-synthesis" (the most often-used method), and through total synthesis.
Hemi-synthesis is performed by extracting diosgenin, a molecule of sapogenin steroids from a vegetable source called dioscorea villosa, or yam (a plant from the yam or "sweet potato family"). The diosgenin molecule can also be extracted from other vegetables, but yams are its richest source. Diosgenin is actually the main ingredient of DHEA, aiding the transformation of certain enzymes into true DHEA molecules.
It is important to know that the enzymes that can carry out the transformation of diosgenin into DHEA are not synthesized by the human body; therefore, using "natural" (non-modified) diosgenin has nothing to do with using DHEA. Be careful if you come across the terms "natural DHEA" or "DHEA precursor" -- these products have absolutely no effect on your body and you are simply being misled by the product marketer.
This is a procedure through which a DHEA molecule is produced by splitting acetic acid, a very simple molecule. Total synthesis is still not very common and makes it possible to produce DHEA without having to import large quantities of yams.
There is an ongoing battle between these two methods. DHEA produced through hemi-synthesis is almost 100% pure. At ANA, to be exact, it is 99.2% pure. Total synthesis likewise allows 100% purity; however, there can be no doubt that this method involves the same efficiency gap that exists between synthesized vitamin C and vitamin C from real oranges.
Should I stop my hormone replacement therapy (HRT) in order to use DHEA, or can I take both at the same time?
It is no problem at all to use both at the same time. Just be sure to find out whether or not you have a DHEA deficiency. The optimum recommended dose for women is 250 to 300 mcg/dl.
Use of DHEA cannot be a replacement for estrogen and progesterone HRT during menopause. In case the two treatments are used at the same time, an overdose of DHEA may cause an imbalance. Actually, DHEA indirectly increases the level of estradiol as well as that of other estrogens in the body, which is why women who use too much DHEA may complain of pain in the breasts before their period. Estradiol itself increases the levels of DHEA and DHEA sulfate.
So, if you are on HRT and wish to benefit from DHEA, a simple test can help you find out if you should be using DHEA or not.
What "foods" are increased by the DHEA level?
The "good fat"! Don't forget that fats are indispensable for the body and are too often downgraded (for example, in animal protein like eggs, poultry, fish or meat).
Can we connect DHEA to other hormones or active ingredients?
Hormones inter-react among themselves; therefore, the efficiency of DHEA can be increased if it is used in combination with other hormones. At the same time, DHEA raises the level of testosterone, of melatonin, or of, for instance, the growth hormone; thus, multi-therapy is actually a good idea. A blood, urine or a saliva test will help adjust the levels of the other essential hormones and determine the correct balance between them.
We also recommend combining DHEA use with other non-hormone products in order to increase its efficiency. For example, antioxidants such as vitamin E, vitamin C, carotenoids, polyphenols (e.g., green tea), as well as other active ingredients, such as shark cartilage, glucosamine and chondroitine.
What does DHEA do?
DHEA works on several levels and helps neutralize some of the problems caused by aging.
- Bones: Helps prevent osteoporosis and increases bone mineral density, particularly in women.
- Skin: Discretely increases production of sebaceous matter, improving skin hydration as well as attenuating age spots.
- Immune System: Boosts the immune response and optimizes the effect of vaccines (especially against the flu).
- Brain: Actually stimulates neurological functions, improves memory and protects brain cells against decay. DHEA may have an effect on stress.
DHEA, the Heart and the Arteries
In case of cardiovascular problems, DHEA, thanks to its conversion into estradiol or testosterone -- two vasodilating hormones -- can help dilate the coronary arteries, increasing the amount of fresh blood transported to the heart and improving its oxygenation.
DHEA decreases the aggregation of the platelets and prevents them from adhering to the arterial walls, helping to reduce the formation of blood clots.
DHEA also helps against atherosclerosis by lessening the thickening of the interior walls of the carotid arteries in the neck because it metabolizes the intermediary estrogen. It neutralizes a portion of the antioxidants generated by metabolic reactions, thus limiting the oxidation that makes the heart and arteries age faster.
Does DHEA help prevent high cholesterol?
Several studies have shown that, especially in men, high levels of DHEA sulfate in the blood usually are accompanied by high HDL cholesterol (good cholesterol) and low levels of LDL cholesterol (bad cholesterol), total cholesterol and triglycerides.
Can DHEA be used for weight loss?
Most studies suggest that low levels of DHEA stimulate obesity. DHEA affects several mechanisms that limit weight gain and fat intake. It increases the levels of various neurotransmitters that reduce appetite and attraction to fat, it can redirect the metabolism and turn fat into muscle by producing male hormones and Growth Factor C.
Does DHEA help in the case of diabetes?
In case of Type 2 diabetes, which mostly occurs with age, DHEA can inhibit excessive insulin secretion, protecting the pancreatic cells from various toxic elements.
Moreover, by increasing lean tissue mass and the number of glucose target-cells, DHEA speeds up sugar absorption and lowers blood sugar. This anti-diabetic effect has been proven to satisfy target-cells as well as other cells such as the red blood cells, the immune system cells, muscle fibers, fat cells and liver cells. Thus, DHEA can protect the target cells in the eye's retina, in the brain, liver and kidneys against damage caused by excessive sugar levels.
Does DHEA help against rheumatism?
DHEA helps against rheumatism in two ways. It stimulates the healing process as well as the joints and the muscles that deteriorate in rheumatic patients. It also has an anti-inflammatory effect as it enhances cortisol's pain-killing properties by preventing it from consuming too much tissue.
Irrespective of age, most rheumatic patients, especially sufferers from inflammatory rheumatism, show low levels of DHEA sulfate in the blood.
Using DHEA Against Wrinkles
The appearance of wrinkles and premature aging of the skin are, to a certain degree, the results of hormone deficiency. The most amazing "face lifting" hormonal treatments consist of: the growth hormone, sex hormones (testosterone and estradiol), DHEA, and melatonin. In this day and age, we have proof positive that the most amazing aesthetic improvements are being achieved by hormone therapies that are adjusted to individual needs by a specialist. The results can be seen after 4 to 6 months of treatment. Wrinkles decrease. What is left are non-curable injuries, such as scars or fibrous tissue. A combination of cosmetics and oral hormone treatment yields surprising results on facial appearance.
What does DHEA do for the skin?
Studies have shown that, particularly when used by women, DHEA can greatly improve skin condition, especially in women with a high level of hormone deficiency, though the results will only be visible after three months of treatment.
As for its appearance, the skin grows smoother due to increased sebum production, softer because of increased fat in the epidermis, firmer because the keratin cells are strengthened. It acquires more consistency because of an increase in collagen components, and finally, the skin acquires higher color because of increased melanin production.
Other noticeable effects are better vascularization and wounds heal better; - more "sexually attractive" skin due to an important increase in androsterone (fragrant cells); better resistance to infections because of increased number of immune skin cells and stimulation of their activity. DHEA also protects the skin against the potential for cancer by blocking "glucose-6-phosphate,'' an enzyme related to certain cancer processes.
Hair Loss and Hormonal Treatment
Extensive hair loss is the result of a significant deficiency in several vital hormones. A physician would prescribe ACTH growth hormone injections in combination with DHEA pills, thyroid hormones, androgen and estrogen, also called multiple hormone therapy. This hormonal treatment is extensive but results in genuine hair re-growth.
DHEA's Effect on Memory
Regular dosages of DHEA noticeably increase memory capacity. This has been demonstrated in our experience with people who had substantial memory retention problems and who showed very low levels of DHEA.
Can DHEA be of help to sufferers from multiple sclerosis (MS)?
According to recent studies, the use of DHEA has no effect toward reducing the neurological scars of MS.
However, it has been noted that people suffering from this disease clearly have below-average levels of DHEA. Taking a DHEA supplement actually helps make them feel in better shape, less fatigued, and improves their ability to deal with stress. It would also seem that the use of DHEA allows MS patients to recover a certain amount of strength in the limbs, particularly the legs.
Does DHEA help fight the AIDS virus?
HIV AIDS multiplies in the body's immune system cells and destroys them. It has been found that DHEA is able to limit the multiplication of the virus within the cells. Unfortunately, as the virus spreads, the blood DHEA level decreases; thus, taking a DHEA supplement is recommended. This cannot, however, be considered a form of therapy.
Under laboratory conditions, DHEA and a synthetic derivative called Imunor 28 inhibit the manifestation of the HIV AIDS virus. DHEA delays the manifestation of this sensitive virus as effectively as an anti-AIDS drug, in the case of a virus that has become resistant.
Can the use of DHEA pose a health risk?
When using hormones, the most important thing is to know exactly what supplement you will be using and to follow the recommended dosage. HORMONES ARE NOT A HEALTH THREAT AS LONG AS THEY ARE USED IN WELL- BALANCED DOSAGES.
Since DHEA is a natural hormone, there have been no reports of noticeable side effects. Dosages higher than 500 mg per day are not advisable.
Hormones are, however, not well considered. The current DHEA fad does not prevent many people from categorizing hormonal remedies as "dangerous."
And why is that?
First of all, because of the abuse of hormone use in the food processing industry, and because hormones derived from human cadavers to treat growth problems proved to be dangerous (this is not longer being practiced). Then there is the myth that using hormones causes cancer. All this is based on a misunderstanding of certain scientific data. The facts are as follows:
Growth Factor C (which is responsible for the growth hormone) in the laboratory prolongs the life span of malignant cells, as well as that of immune system cells. However, the same growth hormone C in the body increases cytotoxic cancer cells.
Estradiol when used alone increases the risk of cervical cancer. This indirect effect is easily counterbalanced by combining estradiol with an adequate dosage of progesterone.
Apparently it has been announced that the incidence of carcinoma of the prostate is increased by the penetration of malignant hormones. However, there are no scientific epidemiological studies that prove the relationship between androgen (such as testosterone) and its manifestation in carcinoma of the prostate. On the contrary, a normal level of androgen actually appears to prevent its appearance.
Then why have the medical profession kept hormones and DHEA under wraps?
Let's listen to two of the best-known international specialists in the hormone field (Dr. Hertogue and Dr. Nabet, "DHEA, the Well-Being Hormone", Chtelet Press): "It is too early a stage. We must wait until more tests have been done and the results of these studies have been confirmed." Doctors are cautious and don't want to give people the wrong advice -- much to their credit! But let's not forget that we don't have a lot of time and that part of the population will be unable to benefit from these studies. It took over 50 years for female hormone menopause treatment to become accepted by the medical profession. The result? Seventy years after the first estrogen treatment (particularly estrogen), less than 20% of European women take advantage of it. Well-intentioned doctors have not always had the time to refer to the numerous studies that have been carried out on DHEA since the 40's!
Does the use of DHEA have any cautions for use?
DHEA use is not recommended for children, pregnant or lactating women, people suffering from benign hypertrophia or carcinoma of the prostate, and women with breast cancer or ovarian carcinoma.
With respect to cancer, please note that DHEA does not cause the disease; it can, however, have a magnifying effect.
What is the role of cancer versus carcinoma of the prostate?
There are no studies that allow us to conclude that daily use of DHEA increases the risk of carcinoma of the prostate. The level of PSA (Prostate-Specific Antigen) in the blood is the indicator of carcinoma of the prostate. PSA has no influence over DHEA sulfate levels or the levels of its metabolites, such as testosterone.
Can a person with carcinoma of the prostate use DHEA?
Since there are no complete studies on this subject, it is advisable to exercise caution. The use of DHEA should be carefully monitored because of a possible resulting increase in the PSA level.
Does DHEA cause weight gain?
The use of DHEA or other hormones does not cause weight gain -- quite the opposite! These treatments reduce fat tissue and increase muscle tone.
Can DHEA treatment cause acne?
The occurrence of acne or oilier hair is an indicator that the dosage should be reduced, not that treatment needs to be discontinued. In most cases, "there is almost no connection between acne and the level of DHEA sulfate or another androgen, unlike other causes (i.e., eating habits, above all) related to a high androgen level, which should be the first factors to consider. A careful diet that is low in milk products (even in yoghurt --try to use calcium tablets instead of calcium itself) and sweets (especially chocolate), usually helps prevent acne in people following DHEA treatment." (Dr Hertogue & Nabet : "DHEA, the Well-Being Hormone", pp. 94-95).
How to Recognize a DHEA Deficiency?
Facial expression is one of the first things that helps detect hormonal deficiency: a bloated face, heavy eyelids, dry and brittle hair. In women these effects are often accompanied by cellulite on the thighs, a paunch, as well as sparse hair growth in the pubic area and a flattened mons veneris (Venus' mound).
Women experience anxiety attacks, low spirits, low libido and sex drive, and constant, unexplained fatigue.
Who should use DHEA?
DHEA use is recommended for the elderly and individuals who experience fatigue due to diseases caused by a depressed immune system. However, persons around age 40 may begin using DHEA, since at 40 the level of hormone production is only half what it should be. This is without considering other factors such as stress, significant dietary deficiencies, sugar or alcohol abuse, smoking, drug abuse, and any other instance of excessive stress, all of which cause the body to age prematurely.
What are adequate DHEA levels in the blood and urine?
The level of DHEA should be measured as well as that of DHEA sulfate (SDHEA).
Blood DHEA: In women, a DHEA level under 200 mcg/dl (micrograms/decilitres) and 150 mcg/dl indicates a deficiency. Studies have shown that in men over 50, DHEA levels below 120 mcg/dl are correlated to a two- or threefold increase in mortality and risk of cardiovascular disease.
When testing urine after 24 hours: DHEA levels below 0.10 ng/24 hours in women and below 0.50 ng in men may indicate a deficiency.
How much DHEA should I use?
The generally-recommended dose is 25 to 50 mg a day for women, and 50 to 75 mg a day for men. Specialists recommend an initial dose of 25 mg per day, together with a blood test after two or three weeks to check the blood DHEA level, as the best way to determine the proper dosage. Men are also advised to check their PSA level, an indicator of prostate disorder.
Always ask for your physician's advice before starting to use DHEA, and never prolong the treatment without first consulting your physician.
Should I consult a physician before starting to use DHEA ?
Even though the use of hormone therapy medicines of proven effectiveness are no longer questioned, most doctors still tend to advise against its use. Practicing physicians are trained to detect disease, not to encourage healthiness; therefore, they practice healing, not preventive medicine. Viewed from the vantage point of healing, the use of hormonal supplements appears to offer benefits that are not confined to cases where a clear deficiency exists.
It must be understood that it is not the use of the medicine that is necessary, but its effects. An individual may start using a supplement if he or she observes the recommended dosages and takes the cautions into account. However, they should consult their physician regularly (i.e., GP, gynecologist or specialist) to check for abnormalities that may or may not be due to the hormonal supplement.
In other words, anyone may start using the hormone supplement of their choice without asking for their physician's permission first (as long as they do so responsibly, follow the recommended dosages and observe the cautions for use), while following their regular medical program.
Are DHEA and the hormones we buy natural substances?
DHEA and other hormones are produced by our own glands and are therefore not medicinal products. This is why hormones do not have any contraindications as opposed to synthetic medicines. They are produced simply by reproducing their exact molecular structure in a laboratory, using today's accurate procedures.
How are hormones "produced"?
There are two ways of producing a hormone: through "hemi-synthesis" (the most often-used method), and through total synthesis.
Hemi-synthesis is performed by extracting diosgenin, a molecule of sapogenin steroids from a vegetable source called dioscorea villosa, or yam (a plant from the yam or "sweet potato family"). The diosgenin molecule can also be extracted from other vegetables, but yams are its richest source. Diosgenin is actually the main ingredient of DHEA, aiding the transformation of certain enzymes into true DHEA molecules.
It is important to know that the enzymes that can carry out the transformation of diosgenin into DHEA are not synthesized by the human body; therefore, using "natural" (non-modified) diosgenin has nothing to do with using DHEA. Be careful if you come across the terms "natural DHEA" or "DHEA precursor" -- these products have absolutely no effect on your body and you are simply being misled by the product marketer.
This is a procedure through which a DHEA molecule is produced by splitting acetic acid, a very simple molecule. Total synthesis is still not very common and makes it possible to produce DHEA without having to import large quantities of yams.
There is an ongoing battle between these two methods. DHEA produced through hemi-synthesis is almost 100% pure. At ANA, to be exact, it is 99.2% pure. Total synthesis likewise allows 100% purity; however, there can be no doubt that this method involves the same efficiency gap that exists between synthesized vitamin C and vitamin C from real oranges.
Should I stop my hormone replacement therapy (HRT) in order to use DHEA, or can I take both at the same time?
It is no problem at all to use both at the same time. Just be sure to find out whether or not you have a DHEA deficiency. The optimum recommended dose for women is 250 to 300 mcg/dl.
Use of DHEA cannot be a replacement for estrogen and progesterone HRT during menopause. In case the two treatments are used at the same time, an overdose of DHEA may cause an imbalance. Actually, DHEA indirectly increases the level of estradiol as well as that of other estrogens in the body, which is why women who use too much DHEA may complain of pain in the breasts before their period. Estradiol itself increases the levels of DHEA and DHEA sulfate.
So, if you are on HRT and wish to benefit from DHEA, a simple test can help you find out if you should be using DHEA or not.
What "foods" are increased by the DHEA level?
The "good fat"! Don't forget that fats are indispensable for the body and are too often downgraded (for example, in animal protein like eggs, poultry, fish or meat).
Can we connect DHEA to other hormones or active ingredients?
Hormones inter-react among themselves; therefore, the efficiency of DHEA can be increased if it is used in combination with other hormones. At the same time, DHEA raises the level of testosterone, of melatonin, or of, for instance, the growth hormone; thus, multi-therapy is actually a good idea. A blood, urine or a saliva test will help adjust the levels of the other essential hormones and determine the correct balance between them.
We also recommend combining DHEA use with other non-hormone products in order to increase its efficiency. For example, antioxidants such as vitamin E, vitamin C, carotenoids, polyphenols (e.g., green tea), as well as other active ingredients, such as shark cartilage, glucosamine and chondroitine.
What does DHEA do?
DHEA works on several levels and helps neutralize some of the problems caused by aging.
- Bones: Helps prevent osteoporosis and increases bone mineral density, particularly in women.
- Skin: Discretely increases production of sebaceous matter, improving skin hydration as well as attenuating age spots.
- Immune System: Boosts the immune response and optimizes the effect of vaccines (especially against the flu).
- Brain: Actually stimulates neurological functions, improves memory and protects brain cells against decay. DHEA may have an effect on stress.
DHEA, the Heart and the Arteries
In case of cardiovascular problems, DHEA, thanks to its conversion into estradiol or testosterone -- two vasodilating hormones -- can help dilate the coronary arteries, increasing the amount of fresh blood transported to the heart and improving its oxygenation.
DHEA decreases the aggregation of the platelets and prevents them from adhering to the arterial walls, helping to reduce the formation of blood clots.
DHEA also helps against atherosclerosis by lessening the thickening of the interior walls of the carotid arteries in the neck because it metabolizes the intermediary estrogen. It neutralizes a portion of the antioxidants generated by metabolic reactions, thus limiting the oxidation that makes the heart and arteries age faster.
Does DHEA help prevent high cholesterol?
Several studies have shown that, especially in men, high levels of DHEA sulfate in the blood usually are accompanied by high HDL cholesterol (good cholesterol) and low levels of LDL cholesterol (bad cholesterol), total cholesterol and triglycerides.
Can DHEA be used for weight loss?
Most studies suggest that low levels of DHEA stimulate obesity. DHEA affects several mechanisms that limit weight gain and fat intake. It increases the levels of various neurotransmitters that reduce appetite and attraction to fat, it can redirect the metabolism and turn fat into muscle by producing male hormones and Growth Factor C.
Does DHEA help in the case of diabetes?
In case of Type 2 diabetes, which mostly occurs with age, DHEA can inhibit excessive insulin secretion, protecting the pancreatic cells from various toxic elements.
Moreover, by increasing lean tissue mass and the number of glucose target-cells, DHEA speeds up sugar absorption and lowers blood sugar. This anti-diabetic effect has been proven to satisfy target-cells as well as other cells such as the red blood cells, the immune system cells, muscle fibers, fat cells and liver cells. Thus, DHEA can protect the target cells in the eye's retina, in the brain, liver and kidneys against damage caused by excessive sugar levels.
Does DHEA help against rheumatism?
DHEA helps against rheumatism in two ways. It stimulates the healing process as well as the joints and the muscles that deteriorate in rheumatic patients. It also has an anti-inflammatory effect as it enhances cortisol's pain-killing properties by preventing it from consuming too much tissue.
Irrespective of age, most rheumatic patients, especially sufferers from inflammatory rheumatism, show low levels of DHEA sulfate in the blood.
Using DHEA Against Wrinkles
The appearance of wrinkles and premature aging of the skin are, to a certain degree, the results of hormone deficiency. The most amazing "face lifting" hormonal treatments consist of: the growth hormone, sex hormones (testosterone and estradiol), DHEA, and melatonin. In this day and age, we have proof positive that the most amazing aesthetic improvements are being achieved by hormone therapies that are adjusted to individual needs by a specialist. The results can be seen after 4 to 6 months of treatment. Wrinkles decrease. What is left are non-curable injuries, such as scars or fibrous tissue. A combination of cosmetics and oral hormone treatment yields surprising results on facial appearance.
What does DHEA do for the skin?
Studies have shown that, particularly when used by women, DHEA can greatly improve skin condition, especially in women with a high level of hormone deficiency, though the results will only be visible after three months of treatment.
As for its appearance, the skin grows smoother due to increased sebum production, softer because of increased fat in the epidermis, firmer because the keratin cells are strengthened. It acquires more consistency because of an increase in collagen components, and finally, the skin acquires higher color because of increased melanin production.
Other noticeable effects are better vascularization and wounds heal better; - more "sexually attractive" skin due to an important increase in androsterone (fragrant cells); better resistance to infections because of increased number of immune skin cells and stimulation of their activity. DHEA also protects the skin against the potential for cancer by blocking "glucose-6-phosphate,'' an enzyme related to certain cancer processes.
Hair Loss and Hormonal Treatment
Extensive hair loss is the result of a significant deficiency in several vital hormones. A physician would prescribe ACTH growth hormone injections in combination with DHEA pills, thyroid hormones, androgen and estrogen, also called multiple hormone therapy. This hormonal treatment is extensive but results in genuine hair re-growth.
DHEA's Effect on Memory
Regular dosages of DHEA noticeably increase memory capacity. This has been demonstrated in our experience with people who had substantial memory retention problems and who showed very low levels of DHEA.
Can DHEA be of help to sufferers from multiple sclerosis (MS)?
According to recent studies, the use of DHEA has no effect toward reducing the neurological scars of MS.
However, it has been noted that people suffering from this disease clearly have below-average levels of DHEA. Taking a DHEA supplement actually helps make them feel in better shape, less fatigued, and improves their ability to deal with stress. It would also seem that the use of DHEA allows MS patients to recover a certain amount of strength in the limbs, particularly the legs.
Does DHEA help fight the AIDS virus?
HIV AIDS multiplies in the body's immune system cells and destroys them. It has been found that DHEA is able to limit the multiplication of the virus within the cells. Unfortunately, as the virus spreads, the blood DHEA level decreases; thus, taking a DHEA supplement is recommended. This cannot, however, be considered a form of therapy.
Under laboratory conditions, DHEA and a synthetic derivative called Imunor 28 inhibit the manifestation of the HIV AIDS virus. DHEA delays the manifestation of this sensitive virus as effectively as an anti-AIDS drug, in the case of a virus that has become resistant.
Can the use of DHEA pose a health risk?
When using hormones, the most important thing is to know exactly what supplement you will be using and to follow the recommended dosage. HORMONES ARE NOT A HEALTH THREAT AS LONG AS THEY ARE USED IN WELL- BALANCED DOSAGES.
Since DHEA is a natural hormone, there have been no reports of noticeable side effects. Dosages higher than 500 mg per day are not advisable.
Hormones are, however, not well considered. The current DHEA fad does not prevent many people from categorizing hormonal remedies as "dangerous."
And why is that?
First of all, because of the abuse of hormone use in the food processing industry, and because hormones derived from human cadavers to treat growth problems proved to be dangerous (this is not longer being practiced). Then there is the myth that using hormones causes cancer. All this is based on a misunderstanding of certain scientific data. The facts are as follows:
Growth Factor C (which is responsible for the growth hormone) in the laboratory prolongs the life span of malignant cells, as well as that of immune system cells. However, the same growth hormone C in the body increases cytotoxic cancer cells.
Estradiol when used alone increases the risk of cervical cancer. This indirect effect is easily counterbalanced by combining estradiol with an adequate dosage of progesterone.
Apparently it has been announced that the incidence of carcinoma of the prostate is increased by the penetration of malignant hormones. However, there are no scientific epidemiological studies that prove the relationship between androgen (such as testosterone) and its manifestation in carcinoma of the prostate. On the contrary, a normal level of androgen actually appears to prevent its appearance.
Then why have the medical profession kept hormones and DHEA under wraps?
Let's listen to two of the best-known international specialists in the hormone field (Dr. Hertogue and Dr. Nabet, "DHEA, the Well-Being Hormone", Châtelet Press): "It is too early a stage. We must wait until more tests have been done and the results of these studies have been confirmed." Doctors are cautious and don't want to give people the wrong advice -- much to their credit! But let's not forget that we don't have a lot of time and that part of the population will be unable to benefit from these studies. It took over 50 years for female hormone menopause treatment to become accepted by the medical profession. The result? Seventy years after the first estrogen treatment (particularly estrogen), less than 20% of European women take advantage of it. Well-intentioned doctors have not always had the time to refer to the numerous studies that have been carried out on DHEA … since the 40's!
Does the use of DHEA have any cautions for use?
DHEA use is not recommended for children, pregnant or lactating women, people suffering from benign hypertrophia or carcinoma of the prostate, and women with breast cancer or ovarian carcinoma.
With respect to cancer, please note that DHEA does not cause the disease; it can, however, have a magnifying effect.
What is the role of cancer versus carcinoma of the prostate?
There are no studies that allow us to conclude that daily use of DHEA increases the risk of carcinoma of the prostate. The level of PSA (Prostate-Specific Antigen) in the blood is the indicator of carcinoma of the prostate. PSA has no influence over DHEA sulfate levels or the levels of its metabolites, such as testosterone.
Can a person with carcinoma of the prostate use DHEA?
Since there are no complete studies on this subject, it is advisable to exercise caution. The use of DHEA should be carefully monitored because of a possible resulting increase in the PSA level.
Does DHEA cause weight gain?
The use of DHEA or other hormones does not cause weight gain -- quite the opposite! These treatments reduce fat tissue and increase muscle tone.
Can DHEA treatment cause acne?
The occurrence of acne or oilier hair is an indicator that the dosage should be reduced, not that treatment needs to be discontinued. In most cases, "…there is almost no connection between acne and the level of DHEA sulfate or another androgen, unlike other causes (i.e., eating habits, above all) related to a high androgen level, which should be the first factors to consider. A careful diet that is low in milk products (even in yoghurt --try to use calcium tablets instead of calcium itself) and sweets (especially chocolate), usually helps prevent acne in people following DHEA treatment." (Dr Hertogue & Nabet : "DHEA, the Well-Being Hormone", pp. 94-95).
